Intra-cytoplasmic sperm injection ICSI
Intra cytoplasmic sperm injection ICSI
is a procedure done under a microscope using micromanipulation devices. It involves
injecting a single sperm into the egg. This technique is used when the sperm is unable to
penetrate the egg wall. If the egg is fertilised, the embryo is inserted into the uterus, in the
same way as for IVF.
The table below describes some of the other less commonly used Intra cytoplasmic sperm injection ICSI procedures.
MESA (Microsurgicalepididymal spermaspiration)
TESE (Testicular spermextraction)
GIFT(Gamete intra-fallopian transfer)
ZIFT (Zygoteintra-fallopian transfer)
Sperm are retrieved directly from the epididymis (area in the testes where
sperm mature and are stored).Fertilisation is then attempted with ICSI
Biopsy of the testes is performed in order to obtain sperm directly from testicular tissue. Fertilisation is then attempted with ICSI.
Follows same procedures as IVF exceptthat fertilisation occurs in the body
(in vivo).Sperm and eggs are placed directly into the fallopian tubes where fertilisation can occur.
Same procedures as IVF except thatfertilised eggs are placed in the fallopian
tubes at a certain stage of embryo development (zygote).
When is it used?
Severe male infertility. Absence of sperm in the ejaculate
Severe male infertility. Absence of sperm in epididymis. Absence of epididymis.
Infertility due to endometriosis and cervical mucus disorders. Religious reasons.
Unexplained infertility. Some cases of male infertility.
Same as for GIFT.Same as for GIFT.